Non-thermal plasma induces immunogenic cell deathin vivoin murine CT26 colorectal tumors
نویسندگان
چکیده
منابع مشابه
Immune and Natural Antibodies to Syngeneic Murine Plasma Cell Tumors
Cytotoxic antibody to a plasma cell tumor antigen was produced in syngeneic BALB mice by immunization with viable or inactivated plasma cell tumors. Antibody with the same specificity was found in the sera of normal BALB and other strains of mice. This natural antibody reacted with an antigen with characteristics indistinguishable from the previously described alloantigen, PC.1, and with viral ...
متن کاملMutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.
The selection of nontumorigenic (turn'), highly immunogenic variants from four different tumorigenic but poorly immuno genic murine tumors by mutagen treatment and cloning is described. Several factors were found to determine the suc cessful nature of this selection procedure including: the nature of the tumor used; the nature of the mutagen; the number of mutagen treatments; and the time at wh...
متن کاملCell damaging by irradiating non-thermal plasma to the water: Mathematical modeling of chemical processes
Recently non-thermal plasma (NTP) is applied for many therapeutic applications. By NTP irradiating to the tissues or cell-lines, the water molecules (H2O) would be also activated leading to generate hydrogen peroxide (H2O2). By irradiating plasma to bio-solution, its main output including vacuum UV to UV causes the photolysis of H2O leading to generat...
متن کاملElectrochemotherapy with bleomycin induces hallmarks of immunogenic cell death in murine colon cancer cells
Electrochemotherapy (ECT) is a local cancer treatment that has been used over the course of more than 2 decades for the removal of cutaneous and subcutaneous tumors. Several lines of evidence support the premise that the immune system is an important factor underlying anticancer treatment efficacy, potentially including patient responses to ECT. The concept of immunogenic cell death (ICD) arose...
متن کاملColon cancer cell treatment with rose bengal generates a protective immune response via immunogenic cell death
Immunotherapeutic approaches to manage patients with advanced gastrointestinal malignancies are desired; however, mechanisms to incite tumor-specific immune responses remain to be elucidated. Rose bengal (RB) is toxic at low concentrations to malignant cells and may induce damage-associated molecular patterns; therefore, we investigated its potential as an immunomodulator in colon cancer. Murin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: OncoImmunology
سال: 2018
ISSN: 2162-402X
DOI: 10.1080/2162402x.2018.1484978